It’s probably going to vary depending on the hunters. Like, if you do hit and runs, they’re worthless unless you get a strike or two. However, you can fight freely until your armor is gone, at which point you can flee to get more armor.
Hunters can mess with this plan, though. For example, in last week’s livestream match the monster engages the hunters, trying to get strikes. The hunters don’t throw their mobile arena until after the monster’s armor gets low. So, just when the monster wants to run, he can’t, and the hunters use the monster’s attempt at a hit and run to trick it and prolong the fight, letting them do serious damage to the monster’s health bar.
So, normally it would be a good idea to do hit and runs, where you attack and try to get strikes until your armor runs out, and then you flee. But if the hunters are smart, they can turn this against you, and in those cases you should probably keep your distance and only attack when the environment is against the hunters’ favor.