Often times I used to press the third key accidentally and waste my abilities in the process.
So one day I decided to use mouse 5, never have I looked back.
Also great layout for monsters mouse 5 for vortex and mouse 4 for banshees.
Great for Goliath movement, awesome for Kraken chains and super agile abduction combo and instant tongue and rock walls. Muahahshhahshshs
Is it considered cheating?